Both players have been forced to pull out of Don Givens' squad because of club comittments.
Defender Painter was part of the Blues squad that played West Ham on Monday evening whilst goalkeeper Doyle, who is currently on-loan at Millwall, is likely to be named in the Lions squad for their Championship game against Hull City at The New Den on Tuesday night.
The Ireland Under 21 side play hosts Madeira tonight (Tuesday) followed by games against Finland tomorrow and Portugal on Friday.