Trailing to two early second half Egyptian goals, the Blues striker pulled a goal back for the Soca Warriors when he met a right wing cross on his chest before hitting home with his left foot from close range.
That goal took John's tally to 20 goals in his last 35 appearnaces for his country.
TnT failed to equalise however and were beaten 2-1 at the Arab Contractors Stadium in Cairo.
T&T: Shaka Hislop, Brent Sancho, Dennis Lawrence, Marvin Andrews, Stokely Mason, Carlos Edwards, Anthony Rougier, Brent Rahim (Anton Pierre, 75), Angus, Stern John, Hector Sam (Cornell Glenn, 38 - Kerry Baptiste, 89).