England manager Sven-Goran Eriksson has decided on a new pairing of Ledley King and John Terry in the centre of the England defence for the game at Newcastles St James Park on Wednesday evening.
Upson will be on the subs bench but the England manager, under FIFA rules, will be restricted to making no more than six substitutions.
Blues striker Emile Heskey withdrew from the squad earlier today suffering with a tight hamstring.
England Starting XI: James, Neville, Cole, Terry, King, Beckham, Butt, Lampard, Gerrard, Owen, Smith.