The Czech Republic international has missed the last three games with a groin injury and abdominal complaint.
But he has returned to training and Blues manager Alex McLeish has confirmed he will be part of the squad to travel to Anfield.
Jiranek had formed an effective partnership with Roger Johnson after the loss of Scott Dann for the second half of the campaign with a hamstring injury.
Strikers Nikola Zigic (groin) and Obafemi Martins (leg) are again ruled out.