Blues' reward for the 3-1 win against Lincoln City in Round Two on Tuesday night is a home tie against Chris Coleman's side at St Andrew's for a place in the last 16.
The tie is likely to be played on Wednesday, 27th October with Blues playing Southampton away in a Premier League fixture on Sunday, 24th October.
For a detailed analysis of the head-to-head between the two sides, click here
Full Draw:
Portsmouth v Leeds
Chelsea v West Ham
Middlesbrough v Coventry
Doncaster v Nott'm Forest
Newcastle v Norwich
Millwall v Liverpool
Burnley v Aston Villa
Southampton v Colchester
Sheff Utd v Watford
Everton v Leicester/Preston
Charlton v Crystal Palace
Bolton v Tottenham
Bournemouth v Cardiff
Man City v Arsenal
Birmingham v Fulham
Crewe v Man Utd